Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599571 | 0.95 | CYP3A4 (0.61) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4650272 | 0.93 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9497372 | 0.93 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL6909734 | 0.84 | CYP3A4 (0.61) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL11535453 | 0.83 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL27358148 | 0.82 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL7697644 | 0.82 | CYP3A4 (0.46) | CYP3A4L3MBTL1LMNALPAR2LPAR3 | |
| SCHEMBL4446173 | 0.81 | CYP3A4 (0.58) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL1699004 | 0.81 | CYP3A4 (0.58) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL8662311 | 0.81 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641888-A | Synthesis of an O,O' -diesters of thiophosphoric acid, an O-ester of thiophosphonic acid, or a thiophosphinic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0723968-A2 | Process for the preparation of thiophosphoric acid 0,0'-diesters and their salts as well as their preparation | BAYER AG (DE) | 1996-07-31 | — | — | EP | disclosed |