Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880355 | 0.95 | TDP1 (0.62) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8896110 | 0.94 | TDP1 (0.60) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8894613 | 0.94 | TDP1 (0.60) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8894015 | 0.92 | TDP1 (0.66) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8881701 | 0.92 | TDP1 (0.66) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL13997917 | 0.90 | TDP1 (0.72) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8896264 | 0.89 | TDP1 (0.58) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8880920 | 0.89 | TDP1 (0.58) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8878852 | 0.89 | TDP1 (0.58) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 | |
| SCHEMBL8895952 | 0.89 | TDP1 (0.58) | TDP1LMNASMN1; SMN2ALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |