Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12360516 | 0.81 | KMT2A (0.41) | GSK3AGSK3BBRD4BRD2MGLL | |
| SCHEMBL181791 | 0.69 | — | — | |
| SCHEMBL12360461 | 0.69 | BRD4 (0.43) | GSK3AGSK3BBRD4BRD2MGLL | |
| SCHEMBL12360507 | 0.65 | BRD4 (0.52) | GSK3AGSK3BBRD4BRD2MGLL | |
| SCHEMBL12360493 | 0.62 | POLB (0.33) | GSK3AGSK3BBRD4BRD2MGLL | |
| SCHEMBL762799 | 0.62 | — | — | |
| SCHEMBL12748060 | 0.60 | — | — | |
| SCHEMBL2487901 | 0.60 | — | — | |
| SCHEMBL686422 | 0.59 | — | — | |
| SCHEMBL762381 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686450-A | Use of N,N'-bis(mercaptoacetyl) hydrazine derivatives as anticataract agents | ALCON LABORATORIES, INC. (US) | 1997-11-11 | — | — | US | claimed |