⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336077 | 1.00 | OR51E2 (0.50) | — | |
| Hydrochloric Acid SCHEMBL3838535 | 0.97 | — | — | |
| SCHEMBL14571204 | 0.92 | CRBN (0.52) | — | |
| SCHEMBL20987588 | 0.92 | CRBN (0.52) | — | |
| SCHEMBL25857953 | 0.92 | CRBN (0.52) | — | |
| SCHEMBL23311429 | 0.92 | CRBN (0.52) | — | |
| SCHEMBL10522634 | 0.90 | CXCR4 (0.45) | — | |
| Azetidine SCHEMBL18173582 | 0.89 | OR51E2 (0.43) | — | |
| SCHEMBL5194 | 0.82 | — | — | |
| SCHEMBL4393228 | 0.82 | CRBN (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| CN-117651700-A | 2-aminobenzothiazole compounds and methods of use | 安进公司 | 2024-03-05 | — | — | CN | claimed |
| CN-116924985-A | Preparation method of fasudil | 山东新时代药业有限公司 | 2023-10-24 | — | — | CN | claimed |
| EP-3684829-B1 | COMPOSITION AND METHOD TO PRODUCE MICROCELLULAR POLYURETHANE FOAM SYSTEMS | BASF SE (DE) | 2023-09-20 | — | — | EP | claimed |
| WO-2022232332-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | AMGEN INC. (US) | 2022-11-03 | — | — | WO | claimed |
| EP-3966206-A1 | HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC (US) | 2022-03-16 | — | — | EP | claimed |
| CN-114072397-A | Heteroaryl aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-02-18 | — | — | CN | claimed |
| US-10105367-B2 | Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2018-10-23 | — | — | US | claimed |
| US-9956224-B2 | — | — | 2018-05-01 | — | — | US | claimed |
| US-20170182052-A1 | THERAPEUTIC THIOPHENE-, FURAN-, AND PYRIDINE-FUSED AZOLOPYRIMIDIN-5-(6H)-ONES | DART NEUROSCIENCE LLC | 2017-06-29 | — | — | US | claimed |
| US-20080166304-A1 | Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums | THE GENERAL HOSPITAL CORPOARTION (US) | 2008-07-10 | — | — | US | claimed |
| WO-2006034219-A2 | INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS | THE GENERAL HOSPITAL CORPORATION (US) | 2006-03-30 | — | — | WO | claimed |
| EP-0436901-B1 | Process for preparing a 1,4-diazacycloheptan-2-one with a mixture of alkylated diamines | GOODRICH CO B F (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | claimed |
| EP-0508181-A1 | Hybrid process for preparing a tri-substituted triazine | THE B.F. GOODRICH COMPANY (US) | 1992-10-14 | — | — | EP | claimed |
| US-5106971-A | Hybrid process for preparing a tri-substituted triazine | THE B. F. GOODRICH COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | claimed |
| US-5034523-A | Process for preparing a 1,4-diazacycloheptan-2-one with a mixture of alkylated diamines | THE B. F. GOODRICH COMPANY (US) | 1991-07-23 | — | — | US | claimed |
| EP-0436901-A2 | Process for preparing a 1,4-diazacycloheptan-2-one with a mixture of alkylated diamines | THE B.F. GOODRICH COMPANY (US) | 1991-07-17 | — | — | EP | claimed |