Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410291 | 0.83 | HRH4 (0.51) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL5913510 | 0.79 | HRH4 (0.62) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL8691873 | 0.79 | HRH4 (0.62) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL5913277 | 0.79 | HRH4 (0.62) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL8691975 | 0.78 | HRH4 (0.61) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL28123555 | 0.77 | CYP3A4 (0.63) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8697115 | 0.76 | ACACB (0.44) | HRH4CYP3A4TAAR1SLC6A4SLC6A2 | |
| SCHEMBL19369643 | 0.74 | CYP3A4 (0.60) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9126115 | 0.72 | CYP3A4 (0.60) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3081031 | 0.72 | ACE (0.66) | HRH4TAAR1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670531-A | ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-09-23 | — | — | US | disclosed |