Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.75 |
| ▸ | PTPRC | P08575 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.53 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.53 |
| ▸ | FGR | P09769 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26348 | 0.86 | ADORA2A (1.00) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| Anthraquinone SCHEMBL11781807 | 0.86 | ADORA2A (1.00) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL1557667 | 0.86 | ADORA2A (1.00) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL29701006 | 0.86 | ADORA2A (1.00) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL29918321 | 0.84 | ADORA2A (0.96) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| Hydrochloric Acid SCHEMBL27499459 | 0.84 | ADORA2A (0.96) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL28027296 | 0.84 | ADORA2A (0.96) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL22529351 | 0.84 | ADORA2A (0.96) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL29944895 | 0.84 | ADORA2A (0.86) | ADORA2APTPRCMAOACSNK1A1CSNK1D | |
| SCHEMBL64318 | 0.84 | ADORA2A (0.86) | ADORA2APTPRCMAOACSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594158-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1997-01-14 | — | — | US | disclosed |
| US-5391749-A | Photoinitiators or photosensitizers | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0344109-B1 | Substituted naphthacene-5,12-diones and their use | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| US-5200513-A | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | BOARD OF REGENTS, UNIVERSITY OF NEBRASKA-LINCOLN (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0523289-A1 | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin | Board of Regents of the University of Nebraska (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5112977-A | Photoinitiators, metallization of polymeric surfaces | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0344109-A2 | Substituted naphthacene-5,12-diones and their use | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |