Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524946 | 0.77 | MAOB (0.36) | — | |
| SCHEMBL1706051 | 0.70 | — | — | |
| SCHEMBL2956758 | 0.65 | IDO1 (0.52) | IDO1PNMTSIGMAR1TAAR1CYP1A2 | |
| SCHEMBL4597173 | 0.65 | — | — | |
| SCHEMBL2418191 | 0.65 | — | — | |
| SCHEMBL1780435 | 0.63 | IDO1 (0.54) | IDO1PNMTSIGMAR1TAAR1ALDH1A1 | |
| SCHEMBL1706017 | 0.63 | — | — | |
| SCHEMBL11043517 | 0.61 | IDO1 (0.52) | IDO1PNMTSIGMAR1TAAR1CYP1A2 | |
| SCHEMBL30271269 | 0.61 | IDO1 (0.52) | IDO1PNMTSIGMAR1TAAR1CYP1A2 | |
| SCHEMBL6022123 | 0.61 | IDO1 (0.52) | IDO1PNMTSIGMAR1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997008169-A1 | FURANONE ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |