Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881701 | 0.90 | TDP1 (0.66) | TDP1APPFFAR1NPC1RAB9A | |
| SCHEMBL8894015 | 0.90 | TDP1 (0.66) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL22832718 | 0.89 | TDP1 (0.81) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8893103 | 0.88 | TDP1 (0.64) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL9367557 | 0.87 | TDP1 (0.92) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8896111 | 0.87 | TDP1 (0.62) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8894637 | 0.87 | TDP1 (0.62) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8895088 | 0.87 | TDP1 (0.62) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8896306 | 0.87 | TDP1 (0.62) | TDP1APPALOX5HCAR2FFAR1 | |
| SCHEMBL8894252 | 0.87 | TDP1 (0.62) | TDP1APPALOX5HCAR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162970-A | Methine and azamethine dyes made from trifluoromethylpyridones | BASF AG (DE) | 1997-10-22 | — | — | CN | disclosed |
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |