SCHEMBL889534

SCHEMBL889534

CC[C@H]1O[C@@H](n2cnc3c(NCc4ccc(OC)cc4[N+](=O)[O-])ncnc32)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 8/20 0.48
ADORA3 P0DMS8 2/20 0.43
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14788954 1.00 SLC29A1 (0.48) SLC29A1ADORA3CYP1A2HPGD
SCHEMBL12570164 0.93 SLC29A1 (0.47) SLC29A1ADORA3CYP1A2HPGD
SCHEMBL889594 0.89 SLC29A1 (0.49) SLC29A1ADORA3CYP1A2HPGD
SCHEMBL888032 0.85 SLC29A1 (0.44) SLC29A1ADORA3CYP1A2HPGD
SCHEMBL14665919 0.83 SLC29A1 (0.67) SLC29A1
SCHEMBL889591 0.83 SLC29A1 (0.67) SLC29A1
SCHEMBL12570160 0.82 SLC29A1 (0.48) SLC29A1ADORA3CYP1A2HPGD
SCHEMBL889701 0.82 SLC29A1 (0.34) SLC29A1ADORA3
SCHEMBL9913214 0.79 NPC1 (0.54) SLC29A1ADORA3
SCHEMBL9913216 0.78 SLC29A1 (0.49) SLC29A1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361727-B2 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing LASERGEN, INC. (US) 2013-01-29 US disclosed
US-20110287427-A1 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2011-11-24 US disclosed