Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.31 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570234 | 0.93 | CASR (0.31) | CASRDNMT1 | |
| SCHEMBL888067 | 0.93 | CASR (0.31) | CASRDNMT1 | |
| SCHEMBL14788998 | 0.93 | CASR (0.31) | CASRDNMT1 | |
| SCHEMBL14680042 | 0.93 | DNMT1 (0.31) | DNMT1 | |
| SCHEMBL16728029 | 0.93 | DNMT1 (0.31) | DNMT1 | |
| SCHEMBL14680063 | 0.92 | DNMT1 (0.31) | DNMT1DNMT3B | |
| SCHEMBL16728043 | 0.92 | DNMT1 (0.31) | DNMT1DNMT3B | |
| SCHEMBL14789000 | 0.89 | CASR (0.31) | CASR | |
| SCHEMBL14664311 | 0.89 | CASR (0.31) | CASR | |
| SCHEMBL14947957 | 0.88 | DNMT1 (0.32) | DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361727-B2 | 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110287427-A1 | 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2011-11-24 | — | — | US | disclosed |