Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894361 | 0.98 | TP53 (0.43) | POLBPLA2G4BMEN1KMT2AEGFR | |
| SCHEMBL8894804 | 0.93 | POLB (0.46) | POLBPLA2G4BEGFRERBB2TP53 | |
| SCHEMBL8910613 | 0.86 | MAPT (0.41) | POLBPLA2G4BMEN1KMT2AMAPT | |
| SCHEMBL8910425 | 0.86 | MAOB (0.42) | POLBPLA2G4BTP53TSHRMAPT | |
| SCHEMBL8894757 | 0.84 | LSS (0.41) | POLBMEN1KMT2ATP53TSHR | |
| SCHEMBL8896481 | 0.84 | MAOB (0.45) | POLBPLA2G4BTP53TSHRMAPT | |
| SCHEMBL8896987 | 0.83 | POLB (0.45) | POLBPLA2G4BEGFRERBB2TP53 | |
| SCHEMBL8895808 | 0.83 | KMT2A (0.43) | POLBPLA2G4BMEN1KMT2ATSHR | |
| SCHEMBL8895163 | 0.82 | POLB (0.37) | POLBPLA2G4BMEN1KMT2AEGFR | |
| SCHEMBL8895035 | 0.81 | POLB (0.45) | POLBPLA2G4BEGFRERBB2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |