Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896007 | 0.95 | TDP1 (0.68) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL9231878 | 0.93 | DPP4 (0.64) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL8898170 | 0.92 | DPP4 (0.62) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL8896857 | 0.90 | TDP1 (0.55) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL10651358 | 0.90 | NPC1 (0.59) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL162806 | 0.87 | HDAC1 (0.62) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL9231881 | 0.86 | HDAC1 (0.60) | NPC1RAB9ATDP1CASP3SENP8 | |
| Phosphine SCHEMBL27480219 | 0.86 | HDAC1 (0.60) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL8896109 | 0.86 | DPP4 (0.55) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL16091085 | 0.85 | TDP1 (0.51) | NPC1RAB9ATDP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |