Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 6/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MTR | Q99707 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187020 | 0.95 | MTTP (0.65) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL6187290 | 0.86 | MTTP (0.77) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL8897758 | 0.85 | MTTP (0.49) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL8891504 | 0.84 | MTTP (0.67) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL6188622 | 0.83 | MTTP (0.62) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL8891745 | 0.83 | MTTP (0.66) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL6605335 | 0.81 | MTTP (0.72) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL6187055 | 0.80 | MTTP (0.64) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL8895351 | 0.80 | MTTP (0.66) | MTTPADRA1ACHRM2ADRA2AADORA3 | |
| SCHEMBL8898374 | 0.80 | MTTP (0.66) | MTTPADRA1ACHRM2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043257-A1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-11-20 | — | — | WO | disclosed |