Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8896839 | 0.99 | TSHR (0.44) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8897831 | 0.90 | TSHR (0.48) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8898311 | 0.88 | TSHR (0.47) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8895548 | 0.85 | F7 (0.46) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8896859 | 0.84 | F7 (0.48) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8896927 | 0.84 | F7 (0.46) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8897814 | 0.83 | F7 (0.47) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL919132 | 0.82 | TSHR (0.57) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8895678 | 0.82 | F7 (0.46) | TSHRF7SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8896311 | 0.82 | MAPT (0.48) | SMN1; SMN2MEN1KMT2AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |