SCHEMBL889582

SCHEMBL889582

CC[C@H]1O[C@@H](n2cnc3c(OC(C)c4ccc(I)cc4[N+](=O)[O-])nc(NC(C)=O)nc32)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.34
KDM4E B2RXH2 1/20 0.33
P2RY1 P47900 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14789029 1.00 SLC29A1 (0.34) SLC29A1KDM4EP2RY1ACHE
SCHEMBL12570255 0.94 SLC29A1 (0.33) SLC29A1KDM4EP2RY1
SCHEMBL12762713 0.94 SLC29A1 (0.33) SLC29A1KDM4EP2RY1
SCHEMBL14789027 0.91 SLC29A1 (0.35) SLC29A1KDM4EP2RY1ACHE
SCHEMBL889712 0.91 SLC29A1 (0.35) SLC29A1KDM4EP2RY1ACHE
SCHEMBL14175897 0.87 P2RY1 (0.34) SLC29A1KDM4EP2RY1
SCHEMBL12570254 0.86 SLC29A1 (0.42) SLC29A1
SCHEMBL889546 0.86 SLC29A1 (0.42) SLC29A1
SCHEMBL12570253 0.85 SLC29A1 (0.34) SLC29A1KDM4EP2RY1ACHE
SCHEMBL12762712 0.85 SLC29A1 (0.34) SLC29A1KDM4EP2RY1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361727-B2 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing LASERGEN, INC. (US) 2013-01-29 US disclosed
US-20110287427-A1 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2011-11-24 US disclosed