Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943153 | 1.00 | HDAC6 (0.51) | HDAC6HDAC1HDAC2PAOXMEN1 | |
| SCHEMBL4676227 | 0.93 | HDAC6 (0.46) | HDAC6HDAC1HDAC2PAOXLMNA | |
| SCHEMBL5555258 | 0.93 | HDAC6 (0.57) | HDAC6HDAC1HDAC2LMNANFKB1 | |
| SCHEMBL3884537 | 0.84 | HDAC6 (0.44) | HDAC6HDAC1HDAC2NFKB1CA14 | |
| SCHEMBL27765894 | 0.83 | HDAC6 (0.46) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL8806268 | 0.80 | HDAC6 (0.41) | HDAC6HDAC1HDAC2NFKB1CA14 | |
| SCHEMBL3884535 | 0.77 | HDAC6 (0.40) | HDAC6HDAC1HDAC2LMNANFKB1 | |
| SCHEMBL38655032 | 0.77 | HDAC6 (0.42) | HDAC6HDAC1HDAC2 | |
| SCHEMBL21952203 | 0.76 | HDAC6 (0.46) | HDAC6HDAC1HDAC2PAOXALDH1A1 | |
| SCHEMBL5287476 | 0.76 | HDAC6 (0.39) | HDAC6HDAC1HDAC2PAOXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681543-A | Polymer-bonded complexing agents and pharmaceutical agents containing them for MRI | SHERING AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5681544-A | Polymer-bonded complexing agents, their complexes and conjugates, processes for their production and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0331616-B1 | Polymer-bonded complexe builders, their complexes, process for their preparation and pharmaceutical agents containing the same | SCHERING AG (DE) | 1995-11-08 | — | — | EP | disclosed |
| EP-0331616-A2 | Polymer-bonded complexe builders, their complexes, process for their preparation and pharmaceutical agents containing the same | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |