SCHEMBL8896224

CC[C@@H](C)[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@H](CCC(N)=O)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	13/20	0.53

▸	KEAP1	Q14145	1/20	0.52

▸	PTH1R	Q03431	1/20	0.51

▸	SCTR	P47872	1/20	0.50

▸	TFPI	P10646	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8895830	0.93	TFPI (0.57)	GLP1RKEAP1PTH1RSCTRTFPI
SCHEMBL8893440	0.93	TFPI (0.57)	GLP1RKEAP1PTH1RSCTRTFPI
SCHEMBL29445552	0.89	GLP1R (0.55)	GLP1RKEAP1PTH1RSCTRTFPI
SCHEMBL30419550	0.89	GLP1R (0.55)	GLP1RKEAP1PTH1RSCTRTFPI
SCHEMBL8894013	0.88	TFPI (0.58)	GLP1RTFPI
SCHEMBL31436710	0.88	GLP1R (0.59)	GLP1RPTH1RSCTR
SCHEMBL8893999	0.88	TFPI (0.53)	GLP1RSCTRTFPI
SCHEMBL30903289	0.87	GLP1R (0.58)	GLP1RKEAP1SCTR
SCHEMBL30176455	0.87	GLP1R (0.61)	GLP1RSCTR
SCHEMBL29836292	0.86	GLP1R (0.60)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5618785-A	ANTIISCHEMIC AGENTS, ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS	CENTOCOR, INC. (US)	1997-04-08	—	—	US	disclosed