Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195651 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL1617515 | 0.80 | MAPT (0.37) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL7576503 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10CLK4 | |
| SCHEMBL16402120 | 0.77 | CSNK1A1 (0.38) | KDM4EALDH1A1GAACSNK1A1CLK4 | |
| SCHEMBL23509034 | 0.75 | HPGD (0.33) | KDM4EALDH1A1HPGDCLK4USP8 | |
| SCHEMBL4424103 | 0.75 | CSNK1A1 (0.46) | KDM4EALDH1A1GAACSNK1A1CLK4 | |
| SCHEMBL8139272 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1GAACSNK1A1CLK4 | |
| SCHEMBL14932502 | 0.75 | PIK3CD (0.33) | KDM4EALDH1A1CLK4PIK3CDPOLB | |
| SCHEMBL2614511 | 0.75 | CYP11B1 (0.35) | KDM4EALDH1A1GAACLK4USP8 | |
| SCHEMBL14932491 | 0.75 | KDM4E (0.32) | KDM4EALDH1A1CLK4RXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | PARP1, PARP11, PARP2 | KDM4E 958/4885ALDH1A1 1171/4885HPGD 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.