Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052590 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL8773013 | 1.00 | — | — | |
| SCHEMBL8896798 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL28044629 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL10046626 | 0.97 | — | — | |
| SCHEMBL8896077 | 0.88 | — | — | |
| SCHEMBL11384575 | 0.85 | TRPV1 (0.50) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL4443550 | 0.85 | TRPV1 (0.50) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL5136479 | 0.85 | TRPV1 (0.50) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL17002461 | 0.85 | TRPV1 (0.50) | TRPV1TRPA1ALDH1A1MAPTSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |