Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 13/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898240 | 0.86 | FDFT1 (0.45) | FDFT1FFAR1 | |
| SCHEMBL8896828 | 0.86 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8898008 | 0.85 | FDFT1 (0.43) | FDFT1FFAR1 | |
| SCHEMBL8897788 | 0.85 | FDFT1 (0.43) | FDFT1FFAR1 | |
| SCHEMBL8897840 | 0.84 | FDFT1 (0.42) | FDFT1FFAR1 | |
| SCHEMBL8824799 | 0.82 | FDFT1 (0.45) | FDFT1 | |
| SCHEMBL8824814 | 0.82 | FDFT1 (0.45) | FDFT1 | |
| SCHEMBL8947188 | 0.74 | FDFT1 (0.45) | FDFT1 | |
| SCHEMBL8947220 | 0.72 | FDFT1 (0.44) | FDFT1 | |
| SCHEMBL9162239 | 0.71 | FDFT1 (0.45) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618964-A | Prodrug esters of phosphonosulfonate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | disclosed |