Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.58 |
| ▸ | MERTK | Q12866 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.55 |
| ▸ | GRK5 | P34947 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898903 | 0.92 | NPY5R (0.77) | NPY5RHTTABCG2MERTKMEN1 | |
| SCHEMBL8890204 | 0.91 | HTT (0.68) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| Hydrochloric Acid SCHEMBL8916013 | 0.91 | NPY5R (0.76) | NPY5RHTTTAAR1ABCG2MERTK | |
| SCHEMBL8890489 | 0.89 | NPY5R (0.60) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| Hydrochloric Acid SCHEMBL8907334 | 0.88 | NPY5R (0.83) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| SCHEMBL8891851 | 0.88 | NPY5R (0.78) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| SCHEMBL8891586 | 0.88 | NPY5R (0.65) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| Hydrochloric Acid SCHEMBL8899399 | 0.87 | NPY5R (0.76) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| SCHEMBL8889167 | 0.87 | NPY5R (0.76) | NPY5RHTTKDM4ETAAR1ABCG2 | |
| Hydrochloric Acid SCHEMBL8901384 | 0.87 | NPY5R (0.64) | NPY5RHTTKDM4ETAAR1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |