SCHEMBL8897781

SCHEMBL8897781

CC(C)(C)COC(=O)OCOP(=O)(OCOC(=O)OCC(C)(C)C)C(CCCc1cccc(Oc2ccccc2)c1)S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 14/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8897991 1.00 FDFT1 (0.50) FDFT1
SCHEMBL8897832 0.99 FDFT1 (0.49) FDFT1
Potassium Ion SCHEMBL8897836 0.91 FDFT1 (0.60) FDFT1
SCHEMBL8898234 0.89 FDFT1 (0.53) FDFT1
SCHEMBL8824807 0.88 FDFT1 (0.53) FDFT1
SCHEMBL762953 0.88 FDFT1 (0.53) FDFT1
SCHEMBL8897788 0.85 FDFT1 (0.43) FDFT1
SCHEMBL8898008 0.85 FDFT1 (0.43) FDFT1
SCHEMBL8896828 0.84 FDFT1 (0.47) FDFT1
SCHEMBL8897840 0.84 FDFT1 (0.42) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618964-A Prodrug esters of phosphonosulfonate squalene synthetase inhibitors and method BRISTOL-MYERS SQUIBB COMPANY (US) 1997-04-08 US disclosed