SCHEMBL889889

SCHEMBL889889

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nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 5/20 0.47
KDM1A O60341 1/20 0.43
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 1/20 0.39
UGT1A1 P22309 1/20 0.39
FNTA P49354 3/20 0.38
FNTB P49356 3/20 0.38
LSS P48449 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889958 0.85 SQLE (0.47) SQLEKDM1AKMT2AMAPTALDH1A1
SCHEMBL12992254 0.80 PAOX (0.48) MAPTALOX15ALDH1A1KDM4E
SCHEMBL889924 0.76 SQLE (0.40) SQLEKDM1AALOX15ALDH1A1FNTA
SCHEMBL889910 0.75 SQLE (0.39) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10574021 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10574029 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10574643 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10574638 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10573962 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1
SCHEMBL10573966 0.75 SQLE (0.41) SQLEKDM1AKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193872-B2 Photo-crosslinkable antifouling compositions, films obtained from said compositions, and corresponding uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2015-11-24 US disclosed
US-20110268689-A1 PHOTO-CROSSLINKABLE ANTIFOULING COMPOSITIONS, FILMS OBTAINED FROM SAID COMPOSITIONS, AND CORRESPONDING USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110268689-A1 PHOTO-CROSSLINKABLE ANTIFOULING COMPOSITIONS, FILMS OBTAINED FROM SAID COMPOSITIONS, AND CORRESPONDING USES ALG1, ALG8, PHOSPHO1 SQLE 94/4885KDM1A 3988/4885KMT2A 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.