Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | SPOP | O43791 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8899336 | 1.00 | TDP1 (0.36) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8900927 | 0.93 | HDAC1 (0.39) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8899151 | 0.93 | HDAC1 (0.38) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8899144 | 0.93 | HDAC1 (0.38) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8900920 | 0.93 | HDAC1 (0.39) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8900667 | 0.93 | TDP1 (0.41) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8900675 | 0.93 | TDP1 (0.41) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8702289 | 0.92 | TDP1 (0.36) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8702295 | 0.92 | TDP1 (0.36) | TDP1KDM4ETSHRHSD17B10HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8899440 | 0.89 | KCNJ1 (0.41) | TDP1KDM4ETSHRHSD17B10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |