Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.51 |
| ▸ | HTR1B | P28222 | 20/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899371 | 0.93 | HTR1D (0.52) | HTR1DHTR1B | |
| SCHEMBL8693154 | 0.81 | HTR1D (0.58) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8900839 | 0.81 | HTR1D (0.56) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8693596 | 0.80 | HTR1D (0.57) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8696786 | 0.79 | HTR1D (0.57) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8695460 | 0.78 | HTR1D (0.58) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8694039 | 0.77 | HTR1D (0.58) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8411444 | 0.77 | HTR1D (0.62) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8470917 | 0.76 | HTR1D (0.47) | HTR1DHTR1BHTR2AHTR1AHTR2C | |
| SCHEMBL8900871 | 0.75 | HTR1D (0.54) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017338-A1 | SUBSTITUTED 1-INDOLYLPROPYL-4-BENZYLPIPERAZINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-15 | — | — | WO | disclosed |