Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900498 | 0.99 | CHRNA7 (0.45) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8711772 | 0.89 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8718311 | 0.89 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8713838 | 0.89 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8711047 | 0.87 | CYP2D6 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8712253 | 0.87 | CYP2D6 (0.48) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8716150 | 0.87 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8716149 | 0.87 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8717079 | 0.87 | CHRNA7 (0.47) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL8714248 | 0.86 | CYP2D6 (0.49) | CHRNA7CHRM3CHRM2CHRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |