Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899630 | 1.00 | NOX1 (0.39) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL8899120 | 0.99 | NOX1 (0.38) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL8714912 | 0.78 | NOX1 (0.39) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL8718311 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL8711772 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| Hydrochloric Acid SCHEMBL8716150 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| Hydrochloric Acid SCHEMBL8717079 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL8713838 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| Hydrochloric Acid SCHEMBL8716149 | 0.71 | CHRNA7 (0.47) | NOX1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL7583938 | 0.67 | CHRNA4 (0.49) | ADRA2AADRA2BADRA2CCHRM3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |