Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888340 | 1.00 | KMT2A (0.57) | KMT2ATLR2EPHX2 | |
| SCHEMBL888338 | 1.00 | KMT2A (0.57) | KMT2ATLR2EPHX2 | |
| SCHEMBL12703680 | 0.89 | KMT2A (0.55) | KMT2AEPHX2 | |
| SCHEMBL12761610 | 0.84 | KMT2A (0.59) | KMT2AEPHX2 | |
| SCHEMBL3140809 | 0.82 | KMT2A (0.73) | KMT2ATLR2EPHX2 | |
| SCHEMBL13525077 | 0.82 | KMT2A (0.73) | KMT2ATLR2EPHX2 | |
| SCHEMBL889867 | 0.81 | KMT2A (0.65) | KMT2ATLR2EPHX2 | |
| SCHEMBL888350 | 0.81 | KMT2A (0.65) | KMT2ATLR2EPHX2 | |
| SCHEMBL888348 | 0.81 | KMT2A (0.65) | KMT2ATLR2EPHX2 | |
| SCHEMBL30861274 | 0.81 | MDM4 (0.52) | KMT2ATLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-6492346-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |