Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309620 | 1.00 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL5400012 | 1.00 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL130783 | 0.98 | CYP1A2 (0.69) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| Benzene SCHEMBL28779493 | 0.95 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| Hydrochloric Acid SCHEMBL28223094 | 0.95 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL31498551 | 0.95 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL28536961 | 0.95 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| Hydrochloric Acid SCHEMBL28060683 | 0.95 | CYP1A2 (0.67) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL29853748 | 0.92 | CYP1A2 (0.58) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL28999606 | 0.92 | CYP1A2 (0.58) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10327907-B2 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | Suture Concepts Inc. (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180028198-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT | SUTURE CONCEPTS INC (US) | 2018-02-01 | — | — | US | disclosed |
| US-9592062-B2 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | ANOVA CORP. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160175104-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT | VERTICAL FUND I, L.P. | 2016-06-23 | — | — | US | disclosed |
| US-9241796-B2 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | FERREE BRET A (US) | 2016-01-26 | — | — | US | disclosed |
| US-9084616-B2 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | ANOVA CORPORATION (US) | 2015-07-21 | — | — | US | disclosed |
| US-8936642-B2 | Methods for treating a defect in the annulus fibrosis | ANOVA CORPORATION (US) | 2015-01-20 | — | — | US | disclosed |
| US-20110288647-A1 | METHODS FOR TREATING A DEFECT IN THE ANNULUS FIBROSIS | ANOVA CORPORATION | 2011-11-24 | — | — | US | disclosed |
| US-20110264224-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT | ANOVA CORPORATION (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110178602-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT | ANOVA CORPORATION | 2011-07-21 | — | — | US | disclosed |
| US-20070038231-A1 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | FERREE BRET A | 2007-02-15 | — | — | US | disclosed |
| US-20070027471-A1 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | VERTICAL FUND I, L.P. | 2007-02-01 | — | — | US | disclosed |
| US-20060247665-A1 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | ANOVA CORP. | 2006-11-02 | — | — | US | disclosed |
| US-20060217747-A1 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | ANOVA CORP. | 2006-09-28 | — | — | US | disclosed |
| EP-1180978-B1 | APPARATUS FOR TREATING DISC HERNIATION | FERREE BRET A (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20040097980-A1 | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft | ANOVA CORP. | 2004-05-20 | — | — | US | disclosed |
| EP-1180978-A4 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION | FERREE BRET A (US) | 2002-10-25 | — | — | EP | disclosed |
| EP-1180978-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION | Ferree, Bret A. (US) | 2002-02-27 | — | — | EP | disclosed |
| US-6245107-B1 | Methods and apparatus for treating disc herniation | ANOVA CORPORATION | 2001-06-12 | — | — | US | disclosed |
| WO-2001010316-A1 | METHODS AND APPARATUS FOR TREATING DISC HERNIATION | FERREE BRET A (US) | 2001-02-15 | — | — | WO | disclosed |