Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.65 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.65 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903565 | 0.84 | TAAR1 (0.58) | CARM1PRMT6PRMT8TAAR1CYP2D6 | |
| SCHEMBL18138028 | 0.84 | CYP2D6 (0.57) | CARM1PRMT6PRMT8TAAR1CYP2D6 | |
| SCHEMBL18378603 | 0.84 | CYP2D6 (0.57) | CARM1PRMT6PRMT8TAAR1CYP2D6 | |
| SCHEMBL13175212 | 0.82 | CYP2D6 (0.56) | CARM1PRMT6PRMT8TAAR1CYP2D6 | |
| SCHEMBL21902241 | 0.81 | CARM1 (0.62) | CARM1PRMT6PRMT8TAAR1RECQL | |
| SCHEMBL19049389 | 0.81 | CARM1 (0.62) | CARM1PRMT6PRMT8TAAR1PRMT1 | |
| SCHEMBL14174779 | 0.81 | CYP2D6 (0.55) | CARM1PRMT6PRMT8TAAR1CYP2D6 | |
| SCHEMBL12124993 | 0.79 | CYP2D6 (0.53) | TAAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL14492296 | 0.79 | CYP2D6 (0.54) | CARM1PRMT6TAAR1CYP2D6CYP2C9 | |
| SCHEMBL14174811 | 0.79 | CYP2D6 (0.54) | TAAR1CYP2D6CYP2C9CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9100276-A | — | — | None | — | — | JP | disclosed |
| EP-3498708-B1 | DEUTERATED 3-(4,5-SUBSTITUTED PYRIMIDINAMINE) PHENYL DERIVATIVES AND APPLICATIONS THEREOF | NANJING CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |
| EP-3747887-A1 | CRYSTAL FORM OF MONOMETHANESULFONATE OF DEUTERATED 3-(4,5-SUBSTITUTED AMINOPYRIMIDINE)PHENYL COMPOUND, AND PREPARATION METHOD THEREFOR | Nanjing Chuangte Pharmaceutical Technology Co., Ltd (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3498708-A1 | DEUTERATED 3-(4,5-SUBSTITUTED PYRIMIDINAMINE) PHENYL DERIVATIVES AND APPLICATIONS THEREOF | Nanjing Chuangte Pharmaceutical Technology Co., Ltd (CN) | 2019-06-19 | — | — | EP | disclosed |
| JP-H09100276-A | (R)-1-ETHYL-4-METHYLHEXAHYDRO-1H-1,4-DIAZEPINE DERIVATIVE AND MEDICINE CONTAINING THE SAME | DAINIPPON PHARMACEUT CO LTD | 1997-04-15 | — | — | JP | disclosed |