SCHEMBL890049

SCHEMBL890049

Cc1ccc2cc3cc4cc5cc6ccccc6cc5cc4cc3cc2c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.84
TDP1 Q9NUW8 2/20 0.84
CYP1A2 P05177 10/20 0.72
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HBB P68871 1/20 0.50
HIF1A Q16665 1/20 0.50
NQO2 P16083 1/20 0.46
ACHE P22303 1/20 0.43
HPGD P15428 2/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NCK1 P16333 1/20 0.41
BACE1 P56817 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889849 1.00 CYP2A6 (0.84) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL1310563 1.00 CYP2A6 (0.84) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL167213 1.00 CYP2A6 (0.84) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL36453 0.92 CYP2A6 (1.00) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL28081333 0.92 CYP2A6 (1.00) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL29372904 0.92 CYP2A6 (1.00) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL2490023 0.91 CYP1A2 (0.87) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL2463834 0.91 CYP1A2 (0.87) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL6888140 0.91 CYP1A2 (0.87) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL6056946 0.91 CYP1A2 (0.87) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10327907-B2 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft Suture Concepts Inc. (US) 2019-06-25 US disclosed
US-20180028198-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT SUTURE CONCEPTS INC (US) 2018-02-01 US disclosed
US-9592062-B2 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft ANOVA CORP. (US) 2017-03-14 US disclosed
US-20160175104-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT VERTICAL FUND I, L.P. 2016-06-23 US disclosed
US-9241796-B2 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft FERREE BRET A (US) 2016-01-26 US disclosed
US-9084616-B2 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft ANOVA CORPORATION (US) 2015-07-21 US disclosed
US-8936642-B2 Methods for treating a defect in the annulus fibrosis ANOVA CORPORATION (US) 2015-01-20 US disclosed
US-20110288647-A1 METHODS FOR TREATING A DEFECT IN THE ANNULUS FIBROSIS ANOVA CORPORATION 2011-11-24 US disclosed
US-20110264224-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT ANOVA CORPORATION (US) 2011-10-27 US disclosed
US-20110178602-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION AND PREVENTING THE EXTRUSION OF INTERBODY BONE GRAFT ANOVA CORPORATION 2011-07-21 US disclosed
US-20070038231-A1 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft FERREE BRET A 2007-02-15 US disclosed
US-20070027471-A1 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft VERTICAL FUND I, L.P. 2007-02-01 US disclosed
US-20060247665-A1 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft ANOVA CORP. 2006-11-02 US disclosed
US-20060217747-A1 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft ANOVA CORP. 2006-09-28 US disclosed
EP-1180978-B1 APPARATUS FOR TREATING DISC HERNIATION FERREE BRET A (US) 2005-05-11 EP disclosed
US-20040097980-A1 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft ANOVA CORP. 2004-05-20 US disclosed
EP-1180978-A4 METHODS AND APPARATUS FOR TREATING DISC HERNIATION FERREE BRET A (US) 2002-10-25 EP disclosed
EP-1180978-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION Ferree, Bret A. (US) 2002-02-27 EP disclosed
US-6245107-B1 Methods and apparatus for treating disc herniation ANOVA CORPORATION 2001-06-12 US disclosed
WO-2001010316-A1 METHODS AND APPARATUS FOR TREATING DISC HERNIATION FERREE BRET A (US) 2001-02-15 WO disclosed