Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8901203 | 0.98 | HTT (0.40) | HTTL3MBTL1MAPTHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL8901209 | 0.98 | HTT (0.40) | HTTL3MBTL1MAPTHPGDKDM4E | |
| SCHEMBL8900100 | 0.87 | PSEN1 (0.39) | HTTCHRNA7MCHR1CHRNB2CHRNB4 | |
| SCHEMBL8900617 | 0.87 | PTGER4 (0.43) | HTTCHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8899708 | 0.86 | PSEN1 (0.39) | HTTMAPTMEN1KMT2ACHRNA7 | |
| SCHEMBL8898300 | 0.85 | PTGER4 (0.43) | HTTCHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8898309 | 0.85 | PTGER4 (0.43) | HTTCHRNA7CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL8900691 | 0.85 | PSEN1 (0.39) | HTTCHRNA7MCHR1CHRNB2CHRNB4 | |
| SCHEMBL8901561 | 0.85 | PSEN1 (0.40) | HTTMAPTMEN1KMT2ACHRNA7 | |
| SCHEMBL8901569 | 0.85 | PSEN1 (0.40) | HTTMAPTMEN1KMT2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |