Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615716 | 0.80 | MEN1 (0.56) | NOX1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7609575 | 0.78 | NOX1 (0.60) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL7609578 | 0.77 | NOX1 (0.48) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL7612631 | 0.74 | NOX1 (0.51) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL751003 | 0.74 | NAMPT (0.47) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8898719 | 0.73 | NOX1 (0.54) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL13370416 | 0.73 | KMT2A (0.65) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL10885421 | 0.72 | HDAC6 (0.63) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL13480582 | 0.71 | MAPT (0.67) | NOX1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL11176488 | 0.71 | NOX1 (0.55) | NOX1ALDH1A1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777471-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |