Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.71 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TDP2 | O95551 | 1/20 | 0.66 |
| ▸ | FGB | P02675 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901953 | 1.00 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL1325196 | 0.95 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| Pentaquine SCHEMBL980723 | 0.85 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| Pentaquine SCHEMBL29596989 | 0.85 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL8891533 | 0.85 | HSP90AA1 (0.98) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL8891233 | 0.85 | HSP90AA1 (0.98) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL8900580 | 0.85 | HSP90AA1 (0.98) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL8891243 | 0.85 | HSP90AA1 (0.98) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL13856507 | 0.84 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL18163920 | 0.84 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006161-A1 | ANTICOCCIDIAL 8-AMINOQUINOLINE DERIVATIVES | PFIZER LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |