Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543729 | 0.75 | TP53 (0.38) | TP53 | |
| Lactic Acid SCHEMBL2976569 | 0.73 | TP53 (0.73) | TP53TSHRSLC7A5 | |
| SCHEMBL4650845 | 0.71 | — | — | |
| SCHEMBL21050040 | 0.70 | TSHR (0.39) | TSHR | |
| Phosphonic Acid SCHEMBL29287705 | 0.69 | TP53 (0.47) | TP53TSHRSLC7A5 | |
| SCHEMBL29096248 | 0.69 | — | — | |
| Lactic Acid SCHEMBL25194 | 0.68 | — | — | |
| Lactic Acid SCHEMBL22341770 | 0.68 | — | — | |
| SCHEMBL17891670 | 0.68 | — | — | |
| Lactic Acid SCHEMBL7469343 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |