SCHEMBL8901260

SCHEMBL8901260

O=C(O)c1ccccc1OC(=O)c1ccccc1Oc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.68
KDM4E B2RXH2 7/20 0.68
LMNA P02545 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C9 P11712 1/20 0.68
ALDH1A1 P00352 5/20 0.65
HPGD P15428 5/20 0.65
CTNNB1 P35222 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 2/20 0.56
ESR1 P03372 1/20 0.56
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
GGT1 P19440 1/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3767070 0.91 KDM4E (0.74) HSD17B10KDM4ELMNACYP1A2CYP2C9
SCHEMBL1798 0.89 CTNNB1 (0.71) HSD17B10KDM4ELMNAALDH1A1HPGD
SCHEMBL767125 0.87 CTNNB1 (0.65) HSD17B10KDM4ELMNACYP1A2CYP2C9
SCHEMBL11875755 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
SCHEMBL8496446 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
Bicarbonate SCHEMBL21517637 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
Bicarbonate SCHEMBL236889 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
SCHEMBL4129945 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
SCHEMBL11407865 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD
Bicarbonate SCHEMBL29943548 0.87 CTNNB1 (0.69) HSD17B10KDM4ELMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670604-A USING AN ALKALI(METAL) BORATE CATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-23 US disclosed
US-5488094-A Process for the preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-30 US disclosed
US-5466775-A Melt polycondensation of a diphenol, compounds of an alkali metal and an alkali earth metal as catalysts DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-14 US disclosed