Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.80 |
| ▸ | UNG | P13051 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.60 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | P4HB | P07237 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899997 | 1.00 | TTR (0.80) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL9095165 | 1.00 | TTR (0.80) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL13926057 | 0.96 | TTR (0.86) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL5020598 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL29759512 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL1927537 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL31317645 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL1927539 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL9075299 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 | |
| SCHEMBL808972 | 0.92 | TTR (0.79) | TTRUNGFBP1SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5521160-A | COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY | HOFFMANN-LA ROCHE INC. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |
| US-4654412-A | UNSATURATED MONOMERS, FIBERS, FILMS, MOLDINGS | CELANESE CORPORATION (US) | 1987-03-31 | — | — | US | disclosed |
| US-4526822-A | Oxygen impermeability | EASTMAN KODAK COMPANY (US) | 1985-07-02 | — | — | US | disclosed |