Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900000 | 1.00 | KMT2A (0.56) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL9243490 | 0.93 | BCHE (0.50) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL9245881 | 0.93 | KDM4E (0.50) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL8900834 | 0.93 | KDM4E (0.50) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL8899998 | 0.93 | KDM4E (0.50) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL719416 | 0.88 | KMT2A (0.73) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL719415 | 0.88 | KMT2A (0.73) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL9248649 | 0.87 | KMT2A (0.61) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL2465289 | 0.85 | KMT2A (0.60) | KMT2AKDM4ETTRMEN1SMN1; SMN2 | |
| SCHEMBL475747 | 0.85 | KMT2A (0.60) | KMT2AKDM4ETTRMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |