Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901622 | 1.00 | PPARG (0.43) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL8901614 | 1.00 | PPARG (0.43) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL4672071 | 0.88 | CYP4F2 (0.44) | PPARGPPARACYP4F2CYP4A11HDAC3 | |
| SCHEMBL4672065 | 0.88 | CYP4F2 (0.44) | PPARGPPARACYP4F2CYP4A11HDAC3 | |
| SCHEMBL5846797 | 0.88 | CYP4F2 (0.44) | PPARGPPARACYP4F2CYP4A11HDAC3 | |
| SCHEMBL3766656 | 0.84 | SMN1; SMN2 (0.45) | ESR2NFKB1NFKB2RELA | |
| SCHEMBL7111420 | 0.83 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL9838132 | 0.83 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL7111422 | 0.83 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL10511106 | 0.81 | PPARG (0.43) | PPARGPPARAPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663194-A | SCHIZOPHRENIA | WYETH | 1997-09-02 | — | — | US | disclosed |