Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900585 | 0.71 | — | — | |
| SCHEMBL8527887 | 0.70 | — | — | |
| SCHEMBL27354248 | 0.69 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL9522522 | 0.69 | — | — | |
| SCHEMBL8903142 | 0.68 | IDO1 (0.33) | SMN1; SMN2 | |
| SCHEMBL9523532 | 0.63 | — | — | |
| SCHEMBL8903248 | 0.63 | AKT1 (0.30) | — | |
| SCHEMBL8900793 | 0.63 | AKT1 (0.34) | — | |
| SCHEMBL8913970 | 0.63 | — | — | |
| SCHEMBL30446083 | 0.62 | SMN1; SMN2 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| CN-1058781-A | New heterocyclic anthracycline hydrocarbon homologue | IAF BIOCHEM INT (CA) | 1992-02-19 | — | — | CN | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |