Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903434 | 1.00 | AKT1 (0.35) | AKT1EPHX2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8903882 | 0.95 | AKT1 (0.36) | AKT1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8902846 | 0.83 | AKT1 (0.33) | AKT1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8902603 | 0.83 | AKT1 (0.36) | AKT1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9755762 | 0.81 | HTT (0.34) | EPHX2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9755783 | 0.80 | HTT (0.36) | EPHX2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8901515 | 0.78 | AKT1 (0.41) | AKT1KDM4ESMN1; SMN2DNMT3BHSP90AA1 | |
| SCHEMBL8902124 | 0.75 | HTT (0.36) | EPHX2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9755777 | 0.75 | HTT (0.36) | EPHX2KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8901690 | 0.75 | HTT (0.36) | EPHX2KDM4EALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |