Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901842 | 1.00 | NPY5R (1.00) | NPY5RMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL13796774 | 0.91 | NPY5R (0.83) | NPY5RMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL13796954 | 0.87 | NPY5R (0.77) | NPY5RMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL8911038 | 0.86 | NPY5R (1.00) | NPY5RAPPBCHEACHEADRA2A | |
| Hydrochloric Acid SCHEMBL8901600 | 0.85 | NPY5R (0.98) | NPY5RAPPBCHEACHEADRA2A | |
| SCHEMBL13796775 | 0.85 | NPY5R (0.73) | NPY5RMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL8900185 | 0.84 | NPY5R (0.80) | NPY5RAPPBCHEACHEADRA2A | |
| SCHEMBL8900188 | 0.84 | NPY5R (0.80) | NPY5RAPPBCHEACHEADRA2A | |
| SCHEMBL13795839 | 0.83 | NPY5R (0.71) | NPY5RALDH1A1SLC6A4GBA1ADRA2A | |
| SCHEMBL13796662 | 0.83 | NPY5R (0.71) | NPY5RMEN1ALDH1A1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |