Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6083381 | 1.00 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL6083675 | 0.97 | — | — | |
| SCHEMBL8901156 | 0.97 | — | — | |
| SCHEMBL8002508 | 0.86 | — | — | |
| SCHEMBL407297 | 0.74 | EPHX1 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL13953119 | 0.74 | EPHX1 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL4839947 | 0.74 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL10524293 | 0.74 | TP53 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL22081103 | 0.74 | EPHX1 (0.41) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL3805027 | 0.74 | EPHX1 (0.41) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093329-A | Intraocular pressure reducing prostaglandin-like 7-oxabicyclo derivatives | ALLERGAN, INC. (US) | 1992-03-03 | — | — | US | claimed |
| US-5675031-A | 4-hydroxy-2-cyclopentenone derivatives and anticancer agent and bone formation accelerator containing the same | TEIJIN LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0448726-B1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0659728-A1 | 4-HYDROXY-2-CYCLOPENTENONE DERIVATIVE AND CARCINOSTATIC AND OSTEOGENESIS PROMOTER CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338844-A | 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient | TEIJIN LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0448726-A1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1991-10-02 | — | — | EP | disclosed |