Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375020 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8965695 | 0.87 | TSHR (0.64) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8965923 | 0.86 | TSHR (0.64) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL22203886 | 0.85 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8965855 | 0.85 | TSHR (0.75) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27800525 | 0.85 | — | — | |
| SCHEMBL33585 | 0.85 | — | — | |
| SCHEMBL27821519 | 0.85 | — | — | |
| SCHEMBL3687266 | 0.84 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14005956 | 0.83 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387568-C | Thermal rectification method and rectifying column | BASF AG (DE) | 2008-05-14 | — | — | CN | disclosed |
| CN-1774412-A | Thermal rectification method and rectifying column | BASF AG (DE) | 2006-05-17 | — | — | CN | disclosed |
| US-5639546-A | CURED LAYER OF A CROSSLINKED POLYMER MATRIX AND DISPERSED COLLOIDAL METAL OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0475592-A2 | Coated article having improved adhesion to organic coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |