Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 7/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902504 | 1.00 | SLCO2A1 (0.53) | SLCO2A1ABCC4MAPTPTGFRTBXA2R | |
| SCHEMBL8902236 | 0.86 | TBXA2R (0.61) | SLCO2A1ABCC4MAPTPTGFRTBXA2R | |
| SCHEMBL8902243 | 0.86 | TBXA2R (0.61) | SLCO2A1ABCC4MAPTPTGFRTBXA2R | |
| SCHEMBL11858593 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL11856696 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL11858572 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL7628321 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL11856692 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL7628327 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 | |
| SCHEMBL11856685 | 0.85 | TBXA2R (0.60) | SLCO2A1MAPTPTGFRTBXA2RPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599837-A | 15-DEOXYPROSTAGLANDINS | SHIONOGI & CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0471856-B1 | 15-DEOXYPROSTAGLANDIN DERIVATIVE | SHIONOGI & CO (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5292754-A | Using 15-deoxyprostaglandin derivative | SHIONOGI & CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0471856-A1 | 15-DEOXYPROSTAGLANDIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |