SCHEMBL890283

SCHEMBL890283

Cc1ccc(Cc2ccc(N3C(=O)c4ccc(C(=O)c5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 3/20 0.56
CA1 P00915 2/20 0.56
CA12 O43570 1/20 0.56
HTT P42858 2/20 0.49
ALDH1A1 P00352 4/20 0.48
NPSR1 Q6W5P4 2/20 0.48
POLB P06746 2/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 2/20 0.48
NPC1 O15118 1/20 0.48
CASP1 P29466 1/20 0.48
RAB9A P51151 1/20 0.48
CASP7 P55210 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
SRD5A2 P31213 1/20 0.47
STAT3 P40763 1/20 0.46
ENPP2 Q13822 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829269 0.96 CA9 (0.50) CA9CA1CA12ALDH1A1NPSR1
SCHEMBL12891168 0.95 CA9 (0.52) CA9CA1CA12HTTALDH1A1
SCHEMBL25712313 0.92 CA9 (0.49) CA9CA1CA12HTTALDH1A1
SCHEMBL17637219 0.92 NPSR1 (0.50) CA9CA1CA12HTTALDH1A1
SCHEMBL7593002 0.92 CA9 (0.65) CA9CA1CA12HTTALDH1A1
SCHEMBL12891172 0.91 CA9 (0.63) CA9CA1CA12HTTALDH1A1
SCHEMBL18905644 0.91 NPSR1 (0.62) CA9CA1CA12HTTALDH1A1
SCHEMBL10098940 0.88 CA9 (0.60) CA9CA1CA12HTTALDH1A1
SCHEMBL17946429 0.87 CA9 (0.72) CA9CA1CA12HTTALDH1A1
SCHEMBL25454879 0.86 ESR1 (0.46) CA9CA1CA12ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786861-B2 High selectivity polyimide/PES blend hollow fiber membrane for gas separations UOP LLC (US) 2023-10-17 US disclosed
US-11786870-B2 CMS membrane, method for the production thereof and use thereof Forschungszentrum Jülich GmbH (DE) 2023-10-17 US disclosed
US-11786861-B2 High selectivity polyimide/PES blend hollow fiber membrane for gas separations UOP LLC (US) 2023-10-17 US disclosed
US-9999861-B2 Carbon molecular sieve membranes for nitrogen/methane separation GEORGIA TECH RESEARCH CORPORATION (US) 2018-06-19 US disclosed
US-20180001269-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-20180001272-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-20180001270-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-20180001271-A1 METALLOPOLYIMIDE PRECURSOR FIBERS FOR AGING-RESISTANT CARBON MOLECULAR SIEVE HOLLOW FIBER MEMBRANES WITH ENHANCED SELECTIVITY L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2018-01-04 US disclosed
US-9808768-B2 Method for synthesis of thin film composite membranes KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2017-11-07 US disclosed
US-20170216778-A1 MEMBRANE MODULE MEMBRANE EXTRACTION TECHNOLOGY LTD. (GB) 2017-08-03 US disclosed
US-8349491-B2 Lithium secondary battery and method of manufacturing the same SANYO ELECTRIC CO., LTD. (JP) 2013-01-08 US disclosed
US-20120223014-A1 POLYMIDE MEMBRANE EVONIK MEMBRANE EXTRACTION TECHNOLOGY LIMITED (GB) 2012-09-06 US disclosed
US-20120142829-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT OF THE SAME DIC CORPORATION (JP) 2012-06-07 US disclosed
US-20110275077-A1 Oligonucleotide-Coated Affinity Membranes and Uses Thereof JAMES WILLIAM 2011-11-10 US disclosed
US-20100181253-A1 CROSS-LINKED POLYIMIDE MEMBRANES EVONIK FIBRES GMBH (AT) 2010-07-22 US disclosed
US-20100113264-A1 CONDUCTIVE SUBSTANCE-ADSORBING RESIN FILM, METHOD FOR PRODUCING CONDUCTIVE SUBSTANCE-ADSORBING RESIN FILM, METAL LAYER-COATED RESIN FILM USING THE SAME, AND METHOD FOR PRODUCING METAL LAYER-COATED RESIN FILM FUJIFILM CORPORATION (JP) 2010-05-06 US disclosed
US-20100038306-A1 ASYMMETRIC MEMBRANES FOR USE IN NANOFILTRATION IMPERIAL INNOVATIONS LIMITED (GB) 2010-02-18 US disclosed
US-20090246632-A1 Lithium secondary battery and method of manufacturing the same Panasonic Energy Co., Ltd. (JP) 2009-10-01 US disclosed
US-20080124631-A1 LITHIUM SECONDARY BATTERY AND METHOD OF MANUFACTURING THE SAME SANYO ELECTRIC CO., LTD. (JP) 2008-05-29 US disclosed
US-7229580-B2 blending a polyphenylene oxide or polysulfone with a polyimide by selectively decomposing the polyimide phase using monoethanolamine or tetramethylammonium hydroxide; narrow pore size distribution; makes membranes for fluid separations, such as microfiltration, ultrafiltration, and gas separation POROGEN CORPORATION (US) 2007-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275077-A1 Oligonucleotide-Coated Affinity Membranes and Uses Thereof CD2BP2, CPSF6, CPSF1 CA9 1566/4885CA1 659/4885CA12 523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.