Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.78 |
| ▸ | PGR | P06401 | 1/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.78 |
| ▸ | HTR2B | P41595 | 1/20 | 0.78 |
| ▸ | MC3R | P41968 | 1/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.78 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.78 |
| ▸ | PTGFR | P43088 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903202 | 1.00 | PDE4D (0.78) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8901976 | 0.95 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8901969 | 0.95 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL18388401 | 0.92 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8903423 | 0.92 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8903428 | 0.92 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617422 | 0.89 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617431 | 0.89 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617428 | 0.89 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| Unoprostone Isopropyl SCHEMBL192726 | 0.88 | PDE4D (1.00) | PDE4DPGRADORA3ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599837-A | 15-DEOXYPROSTAGLANDINS | SHIONOGI & CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0471856-B1 | 15-DEOXYPROSTAGLANDIN DERIVATIVE | SHIONOGI & CO (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5292754-A | Using 15-deoxyprostaglandin derivative | SHIONOGI & CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |