Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903558 | 1.00 | MAPT (0.41) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL8903563 | 1.00 | MAPT (0.41) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL7764698 | 0.92 | MAPT (0.45) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL2450267 | 0.92 | MAPT (0.45) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL2450269 | 0.92 | MAPT (0.45) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9231227 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9804837 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9231233 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL2455167 | 0.87 | MAPT (0.40) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL2455165 | 0.85 | KMT2A (0.53) | MAPTGAALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594133-A | SEPARATING DIASTEREOMERS BY CHROMATOGRAPHY, SPLITTING OFF TRITYL GROUPS, FORMING ACID ADDITION SALTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5556850-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |