Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904185 | 1.00 | AR (0.61) | ARKCNH2SRD5A2 | |
| SCHEMBL4800592 | 0.91 | AR (0.59) | ARKCNH2SRD5A2 | |
| SCHEMBL2639420 | 0.91 | AR (0.59) | ARKCNH2SRD5A2 | |
| SCHEMBL2638512 | 0.91 | AR (0.59) | ARKCNH2SRD5A2 | |
| SCHEMBL4795792 | 0.91 | AR (0.59) | ARKCNH2SRD5A2 | |
| SCHEMBL4797384 | 0.90 | AR (0.55) | ARKCNH2SRD5A2 | |
| SCHEMBL2639989 | 0.90 | AR (0.55) | ARKCNH2SRD5A2 | |
| SCHEMBL2638865 | 0.90 | AR (0.66) | ARKCNH2SRD5A2 | |
| SCHEMBL8903872 | 0.90 | AR (0.55) | ARKCNH2SRD5A2 | |
| SCHEMBL4798868 | 0.90 | AR (0.66) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639741-A | STEROIDS TREATING SKIN DISORDERS | MERCK & CO., INC. (US) | 1997-06-17 | — | — | US | claimed |
| WO-1993023038-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |