Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903867 | 0.83 | POLB (0.47) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL24287193 | 0.81 | POLB (0.42) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL5928375 | 0.81 | POLB (0.42) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL2791944 | 0.78 | POLB (0.41) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL29286049 | 0.78 | POLB (0.41) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL1557570 | 0.77 | KMT2A (0.40) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL21645452 | 0.74 | POLB (0.38) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL22335789 | 0.74 | POLB (0.38) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL5936877 | 0.74 | POLB (0.38) | POLBSMN1; SMN2GAAOPRM1ATM | |
| SCHEMBL10638522 | 0.74 | POLB (0.38) | POLBSMN1; SMN2GAAOPRM1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633243-A | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5527905-A | RELATIVELY FEW SIDE EFFECTS, GOOD SOLUBILITY IN WATER | SANKYO COMPANY, LIMITED (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0290280-B1 | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0290280-A2 | Anti-tumor platinum complexes, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-11-09 | — | — | EP | disclosed |